Electrophysiology & Glaucoma Research
Group Leaders
• John Grigg MBBS FRANZCO FRACS johng@eye.usyd.edu.au
• Alex Klistorner BMed PhD sasha@eye.usyd.edu.au
• Stuart Graham MBBS PhD MS FRANZCO FRACS stuart@eye.usyd.edu.au
• Raymond Garrick MBBS FRACP  
 

John Grigg
     
Alex Klistorner
     
Stuart Graham
     
 
Group Members
• Alessandra Martins MBBS - Postgraduate student  
• Clare Fraser MBBS - Postgraduate student  
• Chandra Balachandran MBBS - Postgraduate student  
• Hemamalini Srinivasan MBBS - Glaucoma Fellow  
• Maria Korsakova MBBS - Electrophysiology Technician  
• Priya Narayan B App VisSc - Electrophysiology Technician  
• Assya Klistorner Electrophysiology Technician  
   
Research Projects

The electrophysiology and glaucoma group continues to provide clinical testing as well as research into new techniques for electrodiagnosis, especially for the detection of glaucoma.

 
Development of Objective Perimetry using the Multifocal Visual Evoked Potential

The AccuMap objective perimeter was developed as a new test for glaucoma at the Save Sight Institute. It relies not upon the patient's subjective responses but on recording visual evoked potentials to map the field of view. We currently have an NHMRC Development Grant for the extension of the technique to use virtual reality goggles as a means of presenting the stimulus. Further projects are possible including software development, signal transmission and wireless technology. Clinical studies with the goggles technology will follow.

 
Clinical Studies in Electrophysiology

We have several current projects using the mVEP examining its role in clinical practice:

 
Glaucoma diagnostics
New techniques using a blue/yellow mVEP stimulus and using binocular simultaneous presentation. Potential project in examining structure and function relationships in glaucoma using OCT imaging, visual fields and electrophysiology testing.
 
Retinal application
Using the multifocal electroretinogram (mERG) to investigate age related macular degeneration.
 
Neuro-ophthalmology
Application to optic neuritis and multiple sclerosis; currently a prospective study is underway. Potential for future clinical trials with immuno-modulating agents in MS. Examination of NF1 and NF2 children.